Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression

Chromodomain Helicase DNA binding protein 5 (CHD5) is a tumor suppressor mapping to 1p36, a genomic region that is frequently deleted in human cancer. Although CHD5 belongs to the CHD family of chromatin-remodeling proteins, whether its tumor-suppressive role involves an interaction with chromatin i...

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Bibliographic Details
Main Authors: Shilpi Paul, Alex Kuo, Thomas Schalch, Hannes Vogel, Leemor Joshua-Tor, W. Richard McCombie, Or Gozani, Molly Hammell, Alea A. Mills
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004342