Direct binding of a hepatitis C virus inhibitor to the viral capsid protein.

Over 130 million people are infected chronically with hepatitis C virus (HCV), which, together with HBV, is the leading cause of liver disease. Novel small molecule inhibitors of Hepatitis C virus (HCV) are needed to complement or replace current treatments based on pegylated interferon and ribaviri...

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Bibliographic Details
Main Authors: Smitha Kota, Virginia Takahashi, Feng Ni, John K Snyder, A Donny Strosberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3289641?pdf=render