Metal Coordination and Biological Screening of a Schiff Base Derived from 8-Hydroxyquinoline and Benzothiazole

Metal Coordination and Biological Screening of a Schiff Base Derived from 8-Hydroxyquinoline and Benzothiazole

Designing new metallodrugs for anticancer therapy is a driving force in the scientific community. Aiming to contribute to this field, we hereby report the development of a Schiff base (H<sub>2</sub>L) derived from the condensation of 2-carbaldehyde-8-hydroxyquinoline with 2-hydrazinobenz...

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Bibliographic Details
Main Authors: Nádia Ribeiro, Pedro F. Farinha, Jacinta O. Pinho, Hugo Luiz, János P. Mészáros, Adelino M. Galvão, João Costa Pessoa, Éva A. Enyedy, Catarina Pinto Reis, Isabel Correia, Maria Manuela Gaspar
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
metal complexes
hydrazone
proton dissociation constants
albumin binding
colorectal cancer
in vitro studies
Online Access:https://www.mdpi.com/1999-4923/14/12/2583

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https://www.mdpi.com/1999-4923/14/12/2583

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