Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression

Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression

Since its original identification as a leukocyte gelatinase/type V collagenase and tumour type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as playing a central role in many aspects of tumour progression. In this review, we relate current concepts concerning the ma...

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Bibliographic Details
Main Authors: Antonietta Rosella Farina, Andrew Reay Mackay
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Cancers
Subjects:
gelatinase B/MMP-9
tumour progression
angiogenesis
metastasis
inflammation
epithelial-mesenchymal transition
invasion
motility
immune surveillance
gelatinase B/MMP-9 inhibitors
Online Access:http://www.mdpi.com/2072-6694/6/1/240

Internet

http://www.mdpi.com/2072-6694/6/1/240

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