Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles

Abstract The SARS-CoV-2 viral infection transforms host cells and produces special organelles in many ways, and we focus on the replication organelles, the sites of replication of viral genomic RNA (vgRNA). To date, the precise cellular localization of key RNA molecules and replication intermediates...

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Bibliographic Details
Main Authors: Leonid Andronov, Mengting Han, Yanyu Zhu, Ashwin Balaji, Anish R. Roy, Andrew E. S. Barentine, Puja Patel, Jaishree Garhyan, Lei S. Qi, W. E. Moerner
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-48991-x