Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling

Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling

Abstract Endotoxin administration is commonly used to study the inflammatory response, and though traditionally given as a bolus injection, it can be administered as a continuous infusion over multiple hours. Several studies hypothesize that the latter better represents the prolonged and pronounced...

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Detalles Bibliográficos
Main Authors: Kristen A. Windoloski, Susanne Janum, Ronan M. G. Berg, Mette S. Olufsen
Formato: Artigo
Idioma:English
Publicado: Wiley 2024-05-01
Series:Experimental Physiology
Subjects:
administration method
continuous infusion
cytokines
data analysis
endotoxin challenge
inflammation
Acceso en liña:https://doi.org/10.1113/EP091552

Internet

https://doi.org/10.1113/EP091552

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