Increased susceptibility to otitis media in a Splunc1-deficient mouse model

Increased susceptibility to otitis media in a Splunc1-deficient mouse model

Otitis media (inflammation of the middle ear) is one of the most common diseases of early childhood. Susceptibility to otitis is influenced by a number of factors, including the actions of innate immune molecules secreted by the epithelia lining the nasopharynx, middle ear and Eustachian tube. The S...

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Bibliographic Details
Main Authors: Jennifer A. Bartlett, David K. Meyerholz, Christine L. Wohlford-Lenane, Paul W. Naumann, Nita H. Salzman, Paul B. McCray
Format: Article
Language:English
Published: The Company of Biologists 2015-05-01
Series:Disease Models & Mechanisms
Subjects:
SPLUNC1
Otitis media
Mouse model
Middle ear
Eustachian tube
Host defense
Online Access:http://dmm.biologists.org/content/8/5/501

Internet

http://dmm.biologists.org/content/8/5/501

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