Comprehensive analysis of amino acid sequence diversity at the F protein cleavage site of Newcastle disease virus in fusogenic activity.

Newcastle disease virus (NDV) is a contagious agent of Newcastle disease in avian species and seriously affects the poultry industry. The cleavage site of the viral F protein (Fcs) is a key determinant of membrane fusion and viral virulence. In this study, we investigated the precise effect of varia...

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Bibliographic Details
Main Authors: Yanhong Wang, Wanqi Yu, Na Huo, Wenbin Wang, Yuanyuan Guo, Qiaolin Wei, Xinglong Wang, Shuxia Zhang, Zengqi Yang, Sa Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0183923&type=printable