Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

<p>Abstract</p> <p>Background</p> <p>It is well known that most neurodegenerative diseases are associated with microglia-mediated inflammation. Our previous research demonstrates that the CD40 signaling is critically involved in microglia-related immune responses in the...

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Bibliographic Details
Main Authors: Bickford Paula, Sanberg Paul R, Bai Yun, Ehrhart Jared, Rezai-Zadeh Kavon, Tan Jun, Shytle R Douglas
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/5/1/41