Does hsa-miR-223-3p from platelet-derived extracellular vesicles regulate tissue factor expression in monocytic cells?

Extracellular vesicles (EVs) released from activated platelets contain microRNAs, the most abundant of which is hsa-miR-223-3p. Endogenous hsa-miR-223-3p suppresses the expression of tissue factor (TF), the initiator of the extrinsic coagulation pathway, in endothelial cells. Monocytes can be induce...

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Bibliographic Details
Main Authors: Mary E. W. Collier, Ashley R. Ambrose, Alison H. Goodall
Format: Article
Language:English
Published: Taylor & Francis Group 2022-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2022.2027903