Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

Radioresistance reduces the antitumor efficiency of radiotherapy and further restricts its clinical application, which is mainly caused by the aggravation of immunosuppressive tumor microenvironment (ITM). Especially tumor-associated macrophages (TAMs) usually display the tumor-promoting M2 phenotyp...

Full description

Bibliographic Details
Main Authors: Yumin Zhang, Zujian Feng, Jinjian Liu, Hui Li, Qi Su, Jiamin Zhang, Pingsheng Huang, Weiwei Wang, Jianfeng Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-10-01
Series:Bioactive Materials
Subjects:
Radioresistance
Tumor-associated macrophage
Polarization
Immunosuppressive tumor microenvironment
Peptide hydrogel
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21006071

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X21006071

Similar Items