Comparison Study of Two Differently Clicked 18F-Folates—Lipophilicity Plays a Key Role

Comparison Study of Two Differently Clicked 18F-Folates—Lipophilicity Plays a Key Role

Within the last decade, several folate-based radiopharmaceuticals for Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) have been evaluated; however, there is still a lack of suitable 18F-folates for clinical PET imaging. Herein, we report the synthesis and ev...

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Bibliographic Details
Main Authors: Kathrin Kettenbach, Laura M. Reffert, Hanno Schieferstein, Stefanie Pektor, Raphael Eckert, Matthias Miederer, Frank Rösch, Tobias L. Ross
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Pharmaceuticals
Subjects:
18F-folates
PET
folic acid
folate receptor
click chemistry
copper-catalyzed click
strain promoted click
Online Access:http://www.mdpi.com/1424-8247/11/1/30

Internet

http://www.mdpi.com/1424-8247/11/1/30

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