HaloTag display enables quantitative single‐particle characterisation and functionalisation of engineered extracellular vesicles

HaloTag display enables quantitative single‐particle characterisation and functionalisation of engineered extracellular vesicles

Abstract Extracellular vesicles (EVs) play key roles in diverse biological processes, transport biomolecules between cells and have been engineered for therapeutic applications. A useful EV bioengineering strategy is to express engineered proteins on the EV surface to confer targeting, bioactivity a...

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Bibliographic Details
Main Authors: Roxana E. Mitrut, Devin M. Stranford, Beth N. DiBiase, Jonathan M. Chan, Matthew D. Bailey, Minrui Luo, Clare S. Harper, Thomas J. Meade, Muzhou Wang, Joshua N. Leonard
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicle
HaloTag
quantification
single vesicle
Online Access:https://doi.org/10.1002/jev2.12469

Internet

https://doi.org/10.1002/jev2.12469

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