AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway

The renin-angiotensin system (RAS) is a paracrine RAS within the central nervous system (CNS) and is closely related to Alzheimer’s disease (AD). The endogenous hexapeptide angiotensin IV (Ang IV), an important component of the brain RAS, was found to rescue cognitive impairment and recover memory i...

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Bibliographic Details
Main Authors: Xiaojin Sun, Yang Deng, Xinxin Fu, Siyu Wang, Rui Duan, Yingdong Zhang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/11/11/1487