Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration

Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration

AbstractBackground Human Immunodeficiency Virus (HIV)/Simian Immunodeficiency Virus (SIV) infection is associated with significant gut damage, similar to that observed in patients with inflammatory bowel disease (IBD). This pathology includes loss of epithelial integrity, microbial translocation, dy...

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Bibliographic Details
Main Authors: Samuel D. Johnson, Nageswara Pilli, Jianshi Yu, Lindsey A. Knight, Maureen A. Kane, Siddappa N. Byrareddy
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Annals of Medicine
Subjects:
Anti-α4β7 antibodies
SIV
short-chain fatty acid (SCFA)
16S rRNA
retinoic acid
gut
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2024.2315224

Internet

https://www.tandfonline.com/doi/10.1080/07853890.2024.2315224

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