SAFETY AND IMMUNOGENICITY OF COLD-ADAPTED RECOMBINANT INFLUENZA VECTOR EXPRESSING ESAT-6 AND AG85А ANTIGENS OF M. TUBERCULOSIS

SAFETY AND IMMUNOGENICITY OF COLD-ADAPTED RECOMBINANT INFLUENZA VECTOR EXPRESSING ESAT-6 AND AG85А ANTIGENS OF M. TUBERCULOSIS

Recombinant viral vectors represent one of the most promising platforms for creating a new generation of vaccines against tuberculosis. We constructed a vaccine candidate based on a cold-adapted influenza vector with a truncated NS1 protein containing an insert of tuberculosis ESAT-6 and Ag85A antig...

Full description

Bibliographic Details
Main Authors: M. V. Sergeeva, A. A. Pulkina, K. A. Vasiliev, E. A. Romanovskaya-Romanko, A. B. Komissarov, O. A. Kuchur, A. Yu. Egorov, L. M. Tsybalova, M. A. Stukova
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2017-12-01
Series:Вопросы вирусологии
Subjects:
vectored vaccine
m. tuberculosis antigen
influenza ns1 protein
cold-adapted influenza vector
recombinant virus
Online Access:https://virusjour.crie.ru/jour/article/viewFile/174/84

Internet

https://virusjour.crie.ru/jour/article/viewFile/174/84

Similar Items