Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO’s substrate binding implicated in obesity

Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO’s substrate binding implicated in obesity

An excessive amount of fat deposition in the body leads to obesity which is a complex disease and poses a generic threat to human health. It increases the risk of various other diseases like diabetes, cardiovascular disease, and multiple types of cancer. Genomic studies have shown that the expressio...

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Bibliographic Details
Main Authors: Rakesh Kumar, Somorjit Singh Ningombam, Rahul Kumar, Harsh Goel, Ajay Gogia, Sachin Khurana, S. V. S. Deo, Sandeep Mathur, Pranay Tanwar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nutrition
Subjects:
obesity
FTO
missense mutation
MD simulation
networking
docking
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.852944/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.852944/full

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