A Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens

ABSTRACT Urinary tract infections (UTIs) pose a major public health burden. The vast majority of UTIs are caused by Gram-negative bacteria. Current culture-based pathogen identification methods may require up to 24 to 48 h of incubation. In this study, we developed and evaluated a method for Gram-ne...

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Bibliographic Details
Main Authors:	Hyojik Yang, Richard D. Smith, Kylie P. Sumner, David R. Goodlett, J. Kristie Johnson, Robert K. Ernst
Format:	Article
Language:	English
Published:	American Society for Microbiology 2022-12-01
Series:	Microbiology Spectrum
Subjects:	lipid A UTI Gram-negative bacteria MALDI-TOF mass spectrometry fast lipid analysis technique MALDI-TOF MS
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.03730-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.03730-22

A Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens

Internet

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