Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Mutations in the leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease (PD) in an autosomal dominant manner. Pathogenic mutations of LRRK2 such as G2019S and R1441C have been observed as common genetic causes of PD. Recently, LRRK2 has been reported to increase the reporter protein synthesi...

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Bibliographic Details
Main Authors: Hyejung Kim, Ilhong Son, Wongi Seol
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2017.1422803