Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice

Abstract The relationships among neuropeptide, calcitonin gene-related peptide (CGRP), and memory formation remain unclear. Here, we showed that the intracerebroventricular administration of CGRP impaired the traumatic fear memories, in a widely studied animal model of post-traumatic stress disorder...

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Bibliographic Details
Main Authors: Narumi Hashikawa-Hobara, Shuta Mishima, Chihiro Okujima, Youdai Shitanishi, Naoya Hashikawa
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86556-w