AMF siRNA treatment of keloid through inhibition signaling pathway of RhoA/ROCK1

A keloid (KD) is a benign dermal fibrotic tumor. Treatment of KDs is challenging and the recurrence rate is high; thus, there is an unmet need to explore new target sites and new treatment methods. As a tumor-associated cytokine, autocrine motility factor (AMF) can effectively stimulate the random a...

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Bibliographic Details
Main Authors: Yi Tian, Lan Jin, Wenhong Zhang, Zumeng Ya, Yuan Cheng, Hongyun Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-06-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304218300631