Impact of <i>N</i>-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients—A Systematic Review

Impact of <i>N</i>-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients—A Systematic Review

Sustained TB infection overproduces reactive oxygen species (ROS) as a host defense mechanism. Research shows ROS is destructive to lung tissue. Glutathione (GSH) neutralizes ROS, although it is consumed. NAC is a precursor of GSH synthesis, and administering an appropriate dose of NAC to patients w...

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Bibliographic Details
Main Authors: Daniel Adon Mapamba, Elingarami Sauli, Lucy Mrema, Julieth Lalashowi, David Magombola, Joram Buza, Willyhelmina Olomi, Robert S. Wallis, Nyanda Elias Ntinginya
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
tuberculosis
<i>N</i>-Acetyl Cysteine (NAC)
antioxidant
glutathione
lung health
culture conversion
Online Access:https://www.mdpi.com/2076-3921/11/11/2298

Internet

https://www.mdpi.com/2076-3921/11/11/2298

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