CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

Summary: Uropathogenic E. coli (UPEC) is a primary organism responsible for urinary tract infections and a common cause of sepsis. Microbially experienced laboratory mice, generated by cohousing with pet store mice, exhibit increased morbidity and mortality to polymicrobial sepsis or lipopolysacchar...

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Bibliographic Details
Main Authors: Matthew D. Martin, Cara Skon-Hegg, Caleb Y. Kim, Julie Xu, Tamara A. Kucaba, Whitney Swanson, Mark J. Pierson, Jesse W. Williams, Vladimir P. Badovinac, Steven S. Shen, Molly A. Ingersoll, Thomas S. Griffith
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013578