Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced <it>in vitro </it>metastatic and transformation activity

<p>Abstract</p> <p>Background</p> <p>Nijmegen breakage syndrome (NBS) is a chromosomal-instability syndrome associated with cancer predisposition, radiosensitivity, microcephaly, and growth retardation. The NBS gene product, NBS1 (p95) or nibrin, is a part of the MRN co...

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Bibliographic Details
Main Authors: Lin Chih-Ta, Wu Chung-Yin, Wu Min-Zu, Wu Kou-Juey
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/1