Engrailed‐1 Promotes Pancreatic Cancer Metastasis

Engrailed‐1 Promotes Pancreatic Cancer Metastasis

Abstract Engrailed‐1 (EN1) is a critical homeodomain transcription factor (TF) required for neuronal survival, and EN1 expression has been shown to promote aggressive forms of triple negative breast cancer. Here, it is reported that EN1 is aberrantly expressed in a subset of pancreatic ductal adenoc...

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Bibliographic Details
Main Authors: Jihao Xu, Jae‐Seok Roe, EunJung Lee, Claudia Tonelli, Keely Y. Ji, Omar W. Younis, Tim D.D. Somervile, Melissa Yao, Joseph P. Milazzo, Herve Tiriac, Anna M. Kolarzyk, Esak Lee, Jean L. Grem, Audrey J. Lazenby, James A. Grunkemeyer, Michael A. Hollingsworth, Paul M. Grandgenett, Alexander D. Borowsky, Youngkyu Park, Christopher R. Vakoc, David A. Tuveson, Chang‐Il Hwang
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
apoptosis
cancer progression
cancer therapeutics
developmental transcription factor
Engrailed‐1
epigenetic reprogramming
Online Access:https://doi.org/10.1002/advs.202308537

Internet

https://doi.org/10.1002/advs.202308537

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