RUNX2 interacts with BRG1 to target CD44 for promoting invasion and migration of colorectal cancer cells

RUNX2 interacts with BRG1 to target CD44 for promoting invasion and migration of colorectal cancer cells

Abstract Background Cancer stem cells (CSCs) play an important role in tumor invasion and metastasis. CD44 is the most commonly used marker of CSCs, with the potential to act as a determinant against the invasion and migration of CSCs and as the key factor in epithelial–mesenchymal transition (EMT)-...

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Bibliographic Details
Main Authors: Xiaodong Yan, Dali Han, Zhiqiang Chen, Chao Han, Wei Dong, Li Han, Lei Zou, Jianbo Zhang, Yan Liu, Jie Chai
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cancer Cell International
Subjects:
RUNX2
BRG1
CD44
Cancer stem cell
Colorectal cancer
Online Access:http://link.springer.com/article/10.1186/s12935-020-01544-w

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http://link.springer.com/article/10.1186/s12935-020-01544-w

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