Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination

Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination

Summary: The elderly are an important target for influenza vaccination, and the determination of factors that underlie immune responsiveness is clinically valuable. We evaluated the immune and metabolic profiles of 205 elderly Singaporeans administered with Vaxigrip. Despite high seroprotection rate...

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Bibliographic Details
Main Authors: Christophe Carre, Glenn Wong, Vipin Narang, Crystal Tan, Joni Chong, Hui Xian Chin, Weili Xu, Yanxia Lu, Michelle Chua, Michael Poidinger, Paul Tambyah, Ma Nyunt, Tze Pin Ng, Daniel Larocque, Catherine Hessler, Nabil Bosco, Laurence Quemeneur, Anis Larbi
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Immunology
Virology
Clinical microbiology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100938X

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http://www.sciencedirect.com/science/article/pii/S258900422100938X

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