Generic sustained release tablets of trimetazidine hydrochloride: Preparation and in vitro–in vivo correlation studies

The aim of the current work was to develop generic sustained-release tablets containing 35 mg trimetazidine dihydrochloride and to establish an in vitro–in vivo correlation that could predict the bioavailability. The marketed sustained release tablet (Vastarel MR) used as reference, a sustained-rele...

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Bibliographic Details
Main Authors: Longmei Wang, Ruihua Feng, Jinhua Gao, Yanwei Xi, Guihua Huang
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615000926