RNA-Based Strategies for Cancer Therapy: In Silico Design and Evaluation of ASOs for Targeted Exon Skipping

Precision medicine in oncology has made significant progress in recent years by approving drugs that target specific genetic mutations. However, many cancer driver genes remain challenging to pharmacologically target (“undruggable”). To tackle this issue, RNA-based methods like antisense oligonucleo...

Full description

Bibliographic Details
Main Authors: Chiara Pacelli, Alice Rossi, Michele Milella, Teresa Colombo, Loredana Le Pera
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/19/14862