Dually Modified Cellulose as a Non-Viral Vector for the Delivery and Uptake of HDAC3 siRNA

Dually Modified Cellulose as a Non-Viral Vector for the Delivery and Uptake of HDAC3 siRNA

RNA interference can be applied to different target genes for treating a variety of diseases, but an appropriate delivery system is necessary to ensure the transport of intact siRNAs to the site of action. In this study, cellulose was dually modified to create a non-viral vector for <i>HDAC3&l...

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Bibliographic Details
Main Authors: Juliana Hülsmann, Henry Lindemann, Jamila Wegener, Marie Kühne, Maren Godmann, Andreas Koschella, Sina M. Coldewey, Thomas Heinze, Thorsten Heinzel
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
guanylated cellulose
biotin
polyplexes
non-viral vectors
siRNA delivery
HDAC3
Online Access:https://www.mdpi.com/1999-4923/15/12/2659

Internet

https://www.mdpi.com/1999-4923/15/12/2659

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