Bisphenol A Analogues Inhibit Human and Rat 11β-Hydroxysteroid Dehydrogenase 1 Depending on Its Lipophilicity

Bisphenol A Analogues Inhibit Human and Rat 11β-Hydroxysteroid Dehydrogenase 1 Depending on Its Lipophilicity

Bisphenol A (BPA) analogues substituted on the benzene ring are widely used in a variety of industrial and consumer materials. However, their effects on the glucocorticoid-metabolizing enzyme 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) remain unclear. The inhibitory effects of 6 BPA analogues on t...

Full description

Bibliographic Details
Main Authors: Hong Wang, Jianmin Sang, Zhongyao Ji, Yang Yu, Shaowei Wang, Yang Zhu, Huitao Li, Yiyan Wang, Qiqi Zhu, Renshan Ge
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
bisphenol analog
glucocorticoid
11β-hydroxysteroid dehydrogenase 1
cortisol
docking analysis
species difference
Online Access:https://www.mdpi.com/1420-3049/28/13/4894

Internet

https://www.mdpi.com/1420-3049/28/13/4894

Similar Items