Shikonin suppresses NEAT1 and Akt signaling in treating paclitaxel-resistant non-small cell of lung cancer

Shikonin suppresses NEAT1 and Akt signaling in treating paclitaxel-resistant non-small cell of lung cancer

Abstract Background The development of paclitaxel-resistance led to the tumor relapse and treatment failure of non-small cell lung cancer. Shikonin has been demonstrated to show anti-cancer activity in many cancer types. The present study aimed to investigate the anti-cancer activity of shikonin in...

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Bibliographic Details
Main Authors: Farong Zang, Yuanquan Rao, Xinhai Zhu, Zhibing Wu, Hao Jiang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Medicine
Subjects:
Shikonin
Drug-resistance
NSCLC
NEAT1
Akt
Online Access:http://link.springer.com/article/10.1186/s10020-020-00152-8

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http://link.springer.com/article/10.1186/s10020-020-00152-8

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