Switched alternative splicing events as attractive features in lung squamous cell carcinoma

Switched alternative splicing events as attractive features in lung squamous cell carcinoma

Abstract Background Alternative splicing (AS) plays important roles in transcriptome and proteome diversity. Its dysregulation has a close affiliation with oncogenic processes. This study aimed to evaluate AS-based biomarkers by machine learning algorithms for lung squamous cell carcinoma (LUSC) pat...

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Bibliographic Details
Main Authors: Boxue He, Cong Wei, Qidong Cai, Pengfei Zhang, Shuai Shi, Xiong Peng, Zhenyu Zhao, Wei Yin, Guangxu Tu, Weilin Peng, Yongguang Tao, Xiang Wang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Cancer Cell International
Subjects:
Alternative splicing
Lung squamous cell carcinoma
Machine learning algorithms
Splicing switch
Biomarkers
Online Access:https://doi.org/10.1186/s12935-021-02429-2

Internet

https://doi.org/10.1186/s12935-021-02429-2

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