Interactome based identification and validation of prefoldin 5-α for prognosing CNS leukemia in B-ALL patients

Abstract We report here the identification and validation of prefoldin 5-alpha (PFDN5-α) for the first time as prognostic biomarker for prediction of central nervous system (CNS) leukemia of B cell acute lymphoblastic leukemia (B-ALL) origin. Since cerebrospinal fluid (CSF) cytology being the gold s...

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Bibliographic Details
Main Authors: Tessy Xavier, Lakshmi Sumitra Vijayachandran, Rumamol Chandran, Ullas Mony, Anitha Augustine, Neeraj Sidharthan, Rema Ganapathy, Pavithran Keechilat, K R. Sundaram, Krishnakumar N. Menon
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19489-7