Cyasterone ameliorates sepsis-related acute lung injury via AKT (Ser473)/GSK3β (Ser9)/Nrf2 pathway

Cyasterone ameliorates sepsis-related acute lung injury via AKT (Ser473)/GSK3β (Ser9)/Nrf2 pathway

Abstract Background Acute lung injury (ALI) is a severe disease that can lead to acute respiratory distress syndrome (ARDS), characterized by intractable hypoxemia, poor lung compliance, and respiratory failure, severely affecting patients' quality of life. The pathogenesis of ALI has not been...

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Bibliographic Details
Main Authors: Miao Lin, Weixi Xie, Dayan Xiong, Siyuan Tang, Xiaoting Huang, Lang Deng, Lei Huang, Xiaohua Zhang, Tingting Zhou, Rui Qian, Qian Zeng, Xiaoxue Sang, Yuyang Luo, Qingzhong Hua, Lu Ren, Wei Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Chinese Medicine
Subjects:
Cyasterone
Acute lung injury
Inflammation
Oxidative stress
Nrf2
AKT
Online Access:https://doi.org/10.1186/s13020-023-00837-2

Internet

https://doi.org/10.1186/s13020-023-00837-2

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