SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

SimiC, a single-cell gene regulatory inference framework is presented that can infer multiple gene regulatory networks across related cell phenotypes, unraveling complex regulatory dynamics.

Bibliographic Details
Main Authors: Jianhao Peng, Guillermo Serrano, Ian M. Traniello, Maria E. Calleja-Cervantes, Ullas V. Chembazhi, Sushant Bangru, Teresa Ezponda, Juan Roberto Rodriguez-Madoz, Auinash Kalsotra, Felipe Prosper, Idoia Ochoa, Mikel Hernaez
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03319-7