Turnover number predictions for kinetically uncharacterized enzymes using machine and deep learning
Abstract The turnover number k cat, a measure of enzyme efficiency, is central to understanding cellular physiology and resource allocation. As experimental k cat estimates are unavailable for the vast majority of enzymatic reactions, the development of accurate computational prediction methods is h...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-39840-4 |