Single-molecule analysis of intracellular insulin granule behavior and its application to analyzing cytoskeletal dependence and pathophysiological implications

Single-molecule analysis of intracellular insulin granule behavior and its application to analyzing cytoskeletal dependence and pathophysiological implications

Introduction: Mobilization of intracellular insulin granules to the plasma membrane plays a crucial role in regulating insulin secretion. However, the regulatory mechanisms of this mobilization process have been poorly understood due to technical limitations. In this study, we propose a convenient a...

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Bibliographic Details
Main Authors: Hiroyasu Hatakeyama, Tomomi Oshima, Shinichiro Ono, Yuichi Morimoto, Noriko Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Physiology
Subjects:
insulin granules
single-molecule analysis
cytoskeleton
actin
microtubules
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1287275/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1287275/full

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