Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP

Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP

Abstract The consolidation of learned information into long-lasting memories requires the strengthening of synaptic connections through de novo protein synthesis. Translation initiation factors play a cardinal role in gating the production of new proteins thereby regulating memory formation. Both po...

Full description

Bibliographic Details
Main Authors: Shane Wiebe, Ziying Huang, Reese Jalal Ladak, Agnieszka Skalecka, Roberta Cagnetta, Jean-Claude Lacaille, Argel Aguilar-Valles, Nahum Sonenberg
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Brain
Subjects:
Glutamatergic neurons
GABAergic neurons
eIF4E homologous protein (4EHP)
Mechanistic target of rapamycin complex 1 (mTORC1)
Online Access:https://doi.org/10.1186/s13041-023-00995-2

Internet

https://doi.org/10.1186/s13041-023-00995-2

Similar Items