Engineering Human Mesenchymal Bodies in a Novel 3D-Printed Microchannel Bioreactor for Extracellular Vesicle Biogenesis

Engineering Human Mesenchymal Bodies in a Novel 3D-Printed Microchannel Bioreactor for Extracellular Vesicle Biogenesis

Human Mesenchymal Stem Cells (hMSCs) and their derived products hold potential in tissue engineering and as therapeutics in a wide range of diseases. hMSCs possess the ability to aggregate into “spheroids”, which has been used as a preconditioning technique to enhance their therapeutic potential by...

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Bibliographic Details
Main Authors: Richard Jeske, Xingchi Chen, Logan Mulderrig, Chang Liu, Wenhao Cheng, Olivia Z. Zeng, Changchun Zeng, Jingjiao Guan, Daniel Hallinan, Xuegang Yuan, Yan Li
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Bioengineering
Subjects:
human mesenchymal stem cells
microchannel
wave motion
3-D aggregates
extracellular vesicle biogenesis
Online Access:https://www.mdpi.com/2306-5354/9/12/795

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https://www.mdpi.com/2306-5354/9/12/795

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