The extrachromosomal circular DNA atlas of aged and young mouse brains

Abstract Extrachromosomal circular DNA (eccDNA) refers to a distinct class of circular DNA molecules that exist independently from linear chromosomal DNA. Extensive evidence has firmly established the significant involvement of eccDNA in cancer initiation, progression, and evolutionary processes. Ho...

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Bibliographic Details
Main Authors: Xiaoning Hong, Jing Li, Peng Han, Shaofu Li, Jiaying Yu, Haoran Zhang, Jiang Li, Yonghui Dang, Xi Xiang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-024-03146-x