SAFlex: A structural alphabet extension to integrate protein structural flexibility and missing data information.

In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of missing residues or uncertainties. An SA aims t...

Full description

Bibliographic Details
Main Authors: Ikram Allam, Delphine Flatters, Géraldine Caumes, Leslie Regad, Vincent Delos, Gregory Nuel, Anne-Claude Camproux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6033379?pdf=render