Identification of signalling pathways activated by Tyro3 that promote cell survival, proliferation and invasiveness in human cancer cells
Tyro3 is a member of the TAM subfamily of receptor tyrosine kinases alongside Axl and MerTK, which are activated by homologous ligands Gas6 and protein S. The TAMs activate signalling pathways that mediate diverse functions including cell survival, proliferation, phagocytosis and immune regulation,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580821002065 |