An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes

An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes

Failure to account for genetic diversity of antigens during vaccine design may lead to vaccine escape. To evaluate the vaccine escape potential of antigens used in vaccines currently in development or clinical testing, we surveyed the genetic diversity, measured population differentiation, and perfo...

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Bibliographic Details
Main Authors: Amed Ouattara, Ankit Dwivedi, Matthew Adams, Amadou Niangaly, Matthew B. Laurens, Myaing M. Nyunt, Christopher V. Plowe, Abdoulaye Djimde, Shannon Takala-Harrison, Joana C. Silva
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Microorganisms
Subjects:
plasmodium
liver-stage
antigen
polymorphism
variants
global diversity
Online Access:https://www.mdpi.com/2076-2607/10/6/1090

Internet

https://www.mdpi.com/2076-2607/10/6/1090

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