Mechanism of Focal Adhesion Kinase Mechanosensing.
Mechanosensing at focal adhesions regulates vital cellular processes. Here, we present results from molecular dynamics (MD) and mechano-biochemical network simulations that suggest a direct role of Focal Adhesion Kinase (FAK) as a mechano-sensor. Tensile forces, propagating from the membrane through...
| Autori principali: | , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Public Library of Science (PLoS)
2015-11-01
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| Serie: | PLoS Computational Biology |
| Accesso online: | https://doi.org/10.1371/journal.pcbi.1004593 |