A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

PB10 IgG<sub>1</sub>, a monoclonal antibody (MAb) directed against an immunodominant epitope on the enzymatic subunit (RTA) of ricin toxin (RT), has been shown to passively protect mice and non-human primates from an aerosolized lethal-dose RT challenge. However, it was recently demonstr...

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Bibliographic Details
Main Authors: Yinghui Rong, Michael Pauly, Adrian Guthals, Henry Pham, Dylan Ehrbar, Larry Zeitlin, Nicholas J. Mantis
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/4/215