Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing

Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing

Epithelial ovarian cancer (EOC) is highly aggressive with poor patient outcomes, and a deeper understanding of ovarian cancer tumorigenesis could help guide future treatment development. We proposed an optimized hit network-target sets model to systematically characterize the underlying pathological...

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Bibliographic Details
Main Authors: Amir Abbas Esmaeilzadeh, Mahdis Kashian, Hayder Mahmood Salman, Marwa Fadhil Alsaffar, Mustafa Musa Jaber, Siamak Soltani, Danial Amiri Manjili, Ahmet Ilhan, Abolfazl Bahrami, John W. Kastelic
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biology
Subjects:
network control
hit network-target sets
driver genes
core module
epithelial ovarian cancer
core nodes
Online Access:https://www.mdpi.com/2079-7737/11/12/1851

Internet

https://www.mdpi.com/2079-7737/11/12/1851

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