Freeze-Drying Ethylcellulose Microparticles Loaded with Etoposide for In Vitro Fast Dissolution and In Vitro Cytotoxicity against Cancer Cell Types, MCF-7 and Caco-2

Freeze-Drying Ethylcellulose Microparticles Loaded with Etoposide for In Vitro Fast Dissolution and In Vitro Cytotoxicity against Cancer Cell Types, MCF-7 and Caco-2

The aim of this study was to improve the solubility of etoposide–ethylcellulose (ET–ETO) microparticles using the freeze-drying technique. Ethylcellulose (EC) microparticles loaded with etoposide (ETO) were prepared with different drug–polymer molar ratios of 1:1, 1:3, 1:6, and 1:20 by the solvent e...

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Bibliographic Details
Main Authors: Ahmed A. H. Abdellatif, Mashari A. Aldhafeeri, Waleed H. Alharbi, Fahad H. Alharbi, Waleed Almutiri, Mohammed A. Amin, Mohammed F. Aldawsari, Hamzah M. Maswadeh
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Applied Sciences
Subjects:
etoposide
freeze-drying
targeted delivery
ethylcellulose
polymer microparticles
Online Access:https://www.mdpi.com/2076-3417/11/19/9066

Internet

https://www.mdpi.com/2076-3417/11/19/9066

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