Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways

Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways

This study investigated the effect and mechanism of chrysosplenol D (CD) on LPS-induced acute lung injury in mice. Histological changes in the lungs were measured by hematoxylin-eosin staining. The levels of IL-6, IL-1β, and TNF-α in the bronchoalveolar lavage fluid were detected by ELISA. The level...

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Bibliographic Details
Main Authors: Qinqin Zhang, Aozi Feng, Mengnan Zeng, Beibei Zhang, Jingya Shi, Yaxin Lv, Bing Cao, Chenxin Zhao, Mengya Wang, Yifan Ding, Xiaoke Zheng
Format: Article
Language:English
Published: SAGE Publishing 2021-10-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259211051069

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https://doi.org/10.1177/17534259211051069

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