Sex-Specific Effects of Early-Life Iron Deficiency and Prenatal Choline Treatment on Adult Rat Hippocampal Transcriptome

Sex-Specific Effects of Early-Life Iron Deficiency and Prenatal Choline Treatment on Adult Rat Hippocampal Transcriptome

Background: Fetal-neonatal iron deficiency (ID) causes long-term neurocognitive and affective dysfunctions. Clinical and preclinical studies have shown that early-life ID produces sex-specific effects. However, little is known about the molecular mechanisms underlying these early-life ID-induced sex...

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Bibliographic Details
Main Authors: Shirelle X. Liu, Tenille K. Fredrickson, Natalia Calixto Mancipe, Michael K. Georgieff, Phu V. Tran
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Nutrients
Subjects:
iron deficiency
choline
sex difference
hippocampus
transcriptome
Online Access:https://www.mdpi.com/2072-6643/15/6/1316

Internet

https://www.mdpi.com/2072-6643/15/6/1316

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